Born with a rare syndrome that prevents her from gaining weight, Elizabeth "Lizzie" Velasquez was first bullied as a child in school for looking different and, later online, as a teenager when she discovered a YouTube video labeling her "The World's Ugliest Woman." The film chronicles unheard stories and details of Lizzie’s physical and emotional journey up to her multi-million viewed TEDx talk, and follows her pursuit from a motivational speaker to Capitol Hill as she lobbies for the first federal anti-bullying bill.

San Francisco: Opens Sept. 25 at the Roxie.