The misadventures of a Spanish crew during the filming of an American movie in Franco's Spain. Penelope Cruz stars as the famous movie star Macarena Granada, who flees the glitz and glamour of 1950s Hollywood to return to her roots in Spain where she has signed on to star in an epic film as Queen Isabella of Spain. The Queen of Spain can be considered as a sequel of The Girl of Your Dreams (La niña de mis ojos, 1998), also written and directed by Trueba. The Girl of Your Dreams unfolded in Germany, as Hitler was in power: a group of Spanish actors travelled all that way to shoot not one, but two folkloric films. Now, these same characters return to the big screen in The Queen of Spain, but this time to make a historical movie, produced by the USA, and shot in Madrid and its surroundings.